I will say that you can get hurt if you do it wrong.Clostridium perfringens
This bug lives in soil, can survive cooking, and can even grow in a freezer. It is not a nice bug to get, and will cause illness in two modes. The live or spored states will cause infection, and the toxins (which are not affected by cooking) will cause their own nasty reaction. I know, I got it from onions! It is also the ONLY under 24 hour responding food born infection. The rest are 48 hours or more (some strains of e-coli take as long as 7 days!)
1. Do not use raw manure. Only well composted manure. (if you use manure at all)
2. Trim the lowest leaves and branches to keep the plant high from the ground.
3. Don't harvest after a heavy rain fall.
4. Don't havest dirty leaves. (the freshest growing tips are best anyway)
5. DO harvest at High Noon. When the sun is fully up is when the plants are in full swing, and the leaves and stems are full of the vigours of life. At night plants store a lot of sugars and the like in their roots so dark havested plant matter is not as good as full light harvested matter.
:D Oh, and DO not grow Cleo! She WILL bite back muahhahahaha