Hi Shel,
Sorbate, sorbic acid, benzoate, benzoic acid, propionate, propionic acid and bisulfite usage levels in food as consumed are regulated by law in the US and Canada.
Propionic acid (and salt) are found in Swiss cheese and found to control certain undesirable bacteria in breads in particular called rope. Propionic acid derives from the breakdown of fats and found in human sweat.
Sorbate and sorbic acid are microbial controlling agent. They are effective against yeast and molds. They are found naturally in certain berries also as a preservative.
Benzoic acid, benzoate have similar effect then sorbate and are also found naturally in berries/plants (particularly cranberries which may explain why they do not rot in bog water).
Benzoic and sorbate work in highly acidic foods (i.e beverages). Propionic acid work is a more neutral pH (i.e breads). These chemicals do not kill microbes but prevent them from multiplying by affecting the membrane making machinery. There are found in nature.
There is FDA identified potential health hazard persistent in the beverage industry where benzoate and vitamin C are found together in an acid environment (fruit beverages, soft drink) it creates benzene a known carcinogen. The reaction is worst in diet products since sugar seems to slow the reaction.
The only really problematic chemical in the list above is Bisulfite because releases sulfite a known allergen and headache maker. It does not exist in nature per se. It's purpose is mostly to preserve the colour of the food like in wine or tomatoes. Sulfite oxidizes (capture oxygen) very easily so it protects fragile colours from fading or browning. Copious amounts (within limits) of sulfite are added to dried fruits and veggies (including sundried tomatoes) to preserve their colour when drying. Sulfites are also antimicrobial and anti fungal but do not affect yeast which is ideal for wine making.
(Erythorbate is used for meat where nitrite/nitrates are used but the chemistry gets complicated)
Luc H.