I think in a dish that uses coffee to enhance the chocolate flavor (chocolate bavarian cream, some chocolate cakes and fillings, etc) I would use instant without any second thoughts. But when it;s the dominant flavor, i feel i can detect a sort of - maybe metallic? - tinge to the instant coffee. I'm not a coffee snob, i drink instant decaf at night (i just think of it as a different drink, like having orzo (toasted barley) which is definitely not to my liking) And though i live in italy, i go out of my way to buy lightly roasted coffee for my american coffee pot for my morning coffee, and never have espresso without milk in it. So it's not out of snobbery.
I just think when you want to make a nice desert, and you have the will and the time, then go for the infusion. But if it doesn;t make that much difference, most people are not going to notice the instant coffee.